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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NIPBL
All Species:
13.64
Human Site:
S877
Identified Species:
33.33
UniProt:
Q6KC79
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6KC79
NP_056199.2
2804
316051
S877
H
R
H
E
S
G
D
S
R
E
R
P
S
S
G
Chimpanzee
Pan troglodytes
XP_001146002
2804
316033
S877
H
R
H
E
S
G
D
S
R
E
R
P
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001096462
2804
316103
S877
H
R
H
E
S
G
D
S
R
E
R
P
S
S
G
Dog
Lupus familis
XP_546344
2804
316124
S877
H
R
H
E
S
G
D
S
R
E
R
P
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6KCD5
2798
315432
D877
H
E
S
G
D
S
R
D
R
P
S
G
E
Q
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509151
2821
317768
E884
L
E
R
K
H
R
H
E
S
G
E
S
R
E
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001154919
2856
323576
V912
S
R
P
N
S
P
R
V
K
Q
E
P
R
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI2
2077
236710
G258
N
Q
V
S
T
N
V
G
Q
I
Q
N
I
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95XZ5
2203
252800
L384
V
T
T
V
L
K
A
L
L
K
L
Q
T
I
K
Sea Urchin
Strong. purpuratus
XP_793995
2228
251283
H408
A
P
A
S
H
Q
Q
H
V
D
N
K
N
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.2
98
N.A.
96.6
N.A.
N.A.
91.8
N.A.
N.A.
68.6
N.A.
26.6
N.A.
25.1
37.9
Protein Similarity:
100
100
99.7
99.1
N.A.
98.7
N.A.
N.A.
95.8
N.A.
N.A.
80.8
N.A.
44.4
N.A.
43.4
54.6
P-Site Identity:
100
100
100
100
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
26.6
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
46.6
N.A.
40
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
40
10
0
10
0
0
0
10
10
% D
% Glu:
0
20
0
40
0
0
0
10
0
40
20
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
40
0
10
0
10
0
10
0
0
50
% G
% His:
50
0
40
0
20
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
10
0
10
0
0
10
10
0
10
0
0
20
% K
% Leu:
10
0
0
0
10
0
0
10
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
0
10
10
10
10
0
% N
% Pro:
0
10
10
0
0
10
0
0
0
10
0
50
0
0
0
% P
% Gln:
0
10
0
0
0
10
10
0
10
10
10
10
0
10
0
% Q
% Arg:
0
50
10
0
0
10
20
0
50
0
40
0
20
0
10
% R
% Ser:
10
0
10
20
50
10
0
40
10
0
10
10
40
50
10
% S
% Thr:
0
10
10
0
10
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
0
10
10
0
0
10
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _